Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Rizatriptan Benzoate Pharmaceutical Secondary Standards; Certified Reference Material | 145202-66-0 | MFCD00866224 | 500MG
Rizatriptan Benzoate Pharmaceutical Secondary Standards; Certified Reference Material | Mol Wt: 391.47 | 145202-66-0 | MFCD00866224 | 500MG
Medchemexpress LLC N-Acetyl mesalazine | 51-59-2 | 99.9% | C9H9NO4 | 50 MG
N-Acetyl mesalazine is the primary intestinal metabolite of 5-Aminosalicylic Acid and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid. It is utilized in the study of diseases such as colitis and colon cancer, demonstrating its ability to scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation.
- Functions as a biomarker for 5-Aminosalicylic Acid efficacy
- Scavenges free radicals and reduces DNA base hydroxylation
- Ameliorates mucosal inflammation
- Useful for studying diseases like colitis and colon cancer
Medchemexpress LLC Capecitabine-d11 | 1132662-08-8 | 99.9% | C15H11D11FN3O6 | 1 MG
Capecitabine-d11 is the deuterium labeled Capecitabine. Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase. It is for research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Glycopyrrolate | 596-51-0 | 99.93% | 398.33 | 25MG
Glycopyrrolate (Glycopyrronium bromide) is a quaternary ammonium derivative and a muscarinic receptor antagonist. It has a bronchoprotective effect and produces a beneficial effect on blood pressure. It can be used for the research of bronchial diseases.
- Functions as a muscarinic receptor antagonist.
- Exhibits a bronchoprotective effect.
- Produces a beneficial effect on blood pressure.
- Can be utilized for research related to bronchial diseases.
Medchemexpress LLC Atazanavir | 198904-31-3 | MFCD09839958 | >98% | 704.86 | 50 MG
Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir is a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death.
- HIV-1 protease inhibitor.
- Substrate and inhibitor of CYP3A4.
- Inhibitor of P-glycoprotein (P-gp).
- SARS-CoV 3CLpro inhibitor (IC50 = 3.49 μM).
- Inhibits cardiac fibrosis and hyperlipidemia.
- Induces malignant glioma death.
Medchemexpress LLC Pantoprazole sodium hydrate | 164579-32-2 | 99.9% | 432.37 | 250 MG
Pantoprazole sodium hydrate is an orally active and potent proton pump inhibitor (PPI). It is a substituted benzimidazole and a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. It improves pH stability and has anti-secretory and anti-ulcer activities. When combined with Doxorubicin, Pantoprazole sodium hydrate significantly increased tumor growth delay.
- Potent proton pump inhibitor
- Improves pH stability
- Possesses anti-secretory activities
- Exhibits anti-ulcer activities
- Can increase tumor growth delay when combined with Doxorubicin
![Medchemexpress LLC 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]- | 119141-88-7 | 96.5% | 345.42 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385914-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]- | 119141-88-7 | 96.5% | 345.42 | 1 ML
Esomeprazole is a potent and orally active proton pump inhibitor that reduces acid secretion by inhibiting the H+, K+-ATPase in gastric parietal cells. It is used for symptomatic gastroesophageal reflux disease research.
- Potent and orally active proton pump inhibitor
- Reduces acid secretion by inhibiting H+, K+-ATPase
- Used for symptomatic gastroesophageal reflux disease research
Cayman Chemical Esomeprazole 250mg
An H+/K+-ATPase inhibitor; reversibly inhibits the activity of the H+/K+-ATPase in an enzyme assay; inhibits histamine-induced gastric acid secretion in rats at 30 mg/kg, s.c.
Medchemexpress LLC Mitotane | 53-19-0 | 99.9% | 320.04 | 500 MG
Mitotane (2,4'-DDD) is an antineoplastic agent used to research adrenocortical carcinoma. This isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT) primarily exerts its adrenocorticolytic effect through lipotoxicity induced by intracellular free cholesterol accumulation. It also has direct pituitary effects on corticotroph cells and can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation.
- Antineoplastic agent for adrenocortical carcinoma research.
- Exerts adrenocorticolytic effect via lipotoxicity.
- Direct pituitary effects on corticotroph cells.
- Induces CYP3A4 gene expression.
- Reduces H295R cell proliferation.
- Reduces TαT1 cell viability.
Medchemexpress LLC Stearyl gallate | 10361-12-3 | 25 G
Stearyl gallate is an alkyl gallate featuring a long 18-carbon alkyl chain. This compound exhibits antioxidant activity and a weak antiviral activity against Herpes Simplex Virus type 1 (HSV-1). It is supplied as a white to off-white solid and is intended for research use only.
- Exhibits antioxidant activity
- Shows weak antiviral activity against HSV-1
- High purity of 99.50%
- Soluble in DMSO (116.67 mg/mL)
Medchemexpress LLC Latanoprost | 130209-82-4 | 1 ML
Latanoprost is a prostaglandin F2α analogue used for glaucoma research. It passes through the cornea and is hydrolyzed by esterase to latanoprost acid, which is an F-prostaglandin (FP) receptor agonist. Latanoprost acid effectively reduces intraocular pressure (IOP) by increasing the outflow of aqueous humor through the uvea.
- Prostaglandin F2α analogue
- Used for glaucoma research
- Passes through the cornea
- Hydrolyzed by esterase to latanoprost acid
- FP receptor agonist
- Reduces intraocular pressure (IOP)
- Increases outflow of aqueous humor through the uvea
Medchemexpress LLC Naproxen etemesil | 385800-16-8 | 99.89% | 336.40 | 1 ML
Naproxen etemesil is a lipophilic, non-acidic, inactive proagent of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay. It is for research use only and not sold to patients.
- Lipophilic, non-acidic, inactive proagent of naproxen.
- Hydrolysed to pharmacologically active Naproxen upon absorption.
- Naproxen is a COX-1 and COX-2 inhibitor.
- IC50s of 8.72 μM for COX-1 and 5.15 μM for COX-2 in cell assay.
- Purity: 99.89%.
Medchemexpress LLC Methyl 1-(2-chloroacetyl)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate | 1987887-92-2 | 25mg
Nintedanib impurity 7 is an impurity of Nintedanib (HY-50904)
Sigma Aldrich Fine Chemicals Biosciences Glimepiride Related Compound B United States Pharmacopeia (USP) Reference Standard | 119018-29-0 | 20MG
Glimepiride Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 351.42 | 119018-29-0 | 20MG
Cayman Chemical Fenbendazole sulfon 10mg
A minor metabolite of fenbendazole; formed by oxidation of oxfendazole, a product of fenbendazole oxidation